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Understanding Systematic Reviews for Orphan Cancer Disorders-A Perspective - Juniper Publishers

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Journal of Trends in Technical and Scientific Research Keywords: Food and drugs; Oncological disorders; Clinical trials; Collaboration; Chronic illness; Disability; Premature death Opinion The United States Food and drugs administration defines a rare disease as any disorder that affects fewer than 200,000 Americans. The European definition is when a disease affects less than 1 in 2,000. These rare diseases poses lot of challenges in treatment decision making [1-3]. In particular Oncological disorders caused multitude of dilemma in clinical decision making. These rare cancers maybe difficult to characterize or define, the recruitment into clinical trials maybe difficult with lack of high quality evidence with very few centers with necessary expertise to manage and do research in these disorders [4-6]. Rare Oncological disorders may cause chronic illness, disability, and often premature death. They are complex with lack of adequate trea...