Juniper Publishers - In Vitro Toxicology, Biodetection and Risk Assessment
Trends in Technical & Scientific Research Opinion Context Food may be assumed as a complex mixture of chemicals. Some are intrinsic components, including macro-and micronutrients, anti-nutrients and inherent toxicants, while others are extrinsic, either added or resulting from natural or industrial sources. In addition, process-related chemicals are formed during processing. To understand the health significance of food chemicals is complex. Many increase but others reduce nutritional value. Some may be associated with beneficial effects. A number have been shown to be harmful, producing toxicity. Therefore, chemicals must be managed to ensure that food is safe. Risk assessment, combining exposure and toxicological information, has been valuable to identify chemicals of concern on which management efforts should focus. Toxicological characterization is a resource-intensive and time-consuming process based on feeding experimental animals with high doses of t...